- Dietary Supplement
- The most biologically active form of folate
- A breakthrough in folate supplementation
- The most bioavailable, active form of folate
- An excellent source of folate for pregnant women
- Supports optimal cardiovascular and nerve function
Folic acid must be converted to its active forms to be used by the body.* This is a multi-step biochemical process that occurs in the intestines and liver. In the presence of intestinal or liver dysfunction this conversion may not occur sufficiently enough to meet the body's needs. Furthermore, up to 60-percent of the U.S. population may have a genetic enzyme defect that makes it difficult for them to convert folic acid into active 5-MTHF. For these individuals and many others, 5-MTHF supplementation may be a more effective method of folate repletion.*
Because deficiencies of folic acid have been linked to low-birth-weight infants and neural tube defects, folic acid requirements double during pregnancy.* The Centers for Disease Control and Prevention recommends folic acid supplementation for all women of childbearing age because the biggest need is during the first trimester, when a woman may not even be aware she is pregnant.* Supplementation with the more active form may be preferable.*
In concert with vitamin B12, 5-MTHF functions as a methyl-group donor involved in the conversion of the amino acid homocysteine to methionine.* Methyl-group donation is vital to many biochemical conversion processes, including the synthesis of serotonin, melatonin, and DNA.*
It is important for women of childbearing age to get enough folic acid – not just those who are planning to become pregnant.* Only 50 percent of pregnancies are planned, so any woman who could become pregnant should get enough folic acid every day – especially before conception and during early pregnancy.*
Since 1984, Thorne Research has set the standard for exceptional formulation and quality manufacturing of premium nutritional supplements. Thorne Research is dedicated to enhancing the health and wellbeing of individuals worldwide by providing innovative, high-quality, research-based nutritional supplements, health diagnostics technology platforms, and the latest in medical education.
With more than 350 products, Thorne Research is recognized by health-care practitioners as a global leader in providing nutritional supplements of the highest quality and purity. Thorne Research is the only nutritional supplement manufacturer that has been authorized to include health and lifestyle content on its website that has been authored by the Mayo Clinic.
Thorne Research products do not contain Genetically Modified Organisms (GMOs) nor any binders, coatings, disintegrants, fillers, or lubricants (including magnesium stearate) that could impair absorption. In addition, Thorne Research has received the prestigious NSF International general Good Manufacturing Practices (GMP) and Certified for Sport® certifications.
Select products that receive the NSF Certified for Sport® certification enables athletes, coaches, and trainers to make informed decisions when choosing nutritional supplements for sports performance.
Suggested Use Take 1 capsule one to three times daily or as recommended by your health-care practitioner.